For a long time we have known what means are essential for achieving embryonic development. However, in the last few years advances in the knowledge of cellular metabolism and factors possibly affecting the correct evolution of embryos have allowed us to improve the quality of in-vitro developed embryos.
For these improvements to come about, it is extremely important that the work in the in-vitro fertilization laboratory is carried out with absolute perfection so as to obtain embryos with the highest potential for implantation. By doing so we can guarantee that each embryo is in the most suitable conditions at all times - changing it to the most appropriate pre-prepared culture medium for each phase of development, having the incubators at perfect temperature and gas proportioned conditions, maintaining the temperature during the whole process from the moment of obtaining the embryos until their implant, and so on.
All of these apparently obvious circumstances are only carried out in the stricter and most modern laboratories with the most advanced knowledge in techniques and research. Only in this way, can we offer the best results.
Apart from these laboratory conditions, modifications in the techniques of IVF and ICSI exist that allow better embryonic quality, such as in the position of the polar corpuscle at the moment of the microinjection or in the length of time the oocytes remain with the sperm when an IVF is performed.
Other techniques could improve the prognosis of implantation of some embryos of low quality, such as the aspiration of extra cellular fragments or the Attended Hatching (artificial breakage of the pellucida zone).